Abstract This study presents a novel and simple method to modify the microstructure of bacterial cellulose (BC) hydrogel. BC specimens were produced using Gluconacetobacterxylinus ATCC 53582, then cut into cross-shape specimens and subjected to biaxial cyclic tension in a displacement-control mode. Microstructural changes in the tested specimens were recorded during a biaxial deformation process. The effect of biaxial load on microstructure of BC hydrogel was investigated to understand deformation and fracture mechanisms of a BC fibrous network. The obtained knowledge reveals the fundamental principles of microstructural modifications, which could enhance biological performance of such hydrogels. The mechanically re-constructed BC specimens demonstrated a relatively homogeneous micro-porous structure with an average pore size of 100 μm.

中文翻译：

---

双轴循环张力下细菌纤维素水凝胶的机械改性

摘要 本研究提出了一种新颖且简单的方法来修饰细菌纤维素 (BC) 水凝胶的微观结构。BC 样品使用 Gluconacetobacterxylinus ATCC 53582 生产，然后切成十字形样品并以位移控制模式经受双轴循环拉伸。在双轴变形过程中记录了测试样品的微观结构变化。研究了双轴载荷对 BC 水凝胶微观结构的影响，以了解 BC 纤维网络的变形和断裂机制。获得的知识揭示了微结构修饰的基本原理，这可以增强此类水凝胶的生物性能。机械重建的 BC 样品表现出相对均匀的微孔结构，平均孔径为 100 μm。