Researches dedicated to reactive oxygen species (ROS) had been performed for decades, yet the outcomes remain controversial. With the relentless effort of studies, researchers have explored the role of ROS in biosystem and various diseases. ROS are beneficial for biosystem presenting as signalling molecules and enhancing immunologic defence. However, they also have harmful effects such as causing tissue and organ damages. The results are controversial in studies focusing on ROS and ROS-related diseases by regulating ROS with inhibitors or promotors. These competing results hindered the process for further investigation of the specific mechanisms lying behind. The opinions presented in this review interpret the researches of ROS from a different dimension that might explain the competing results of ROS introduced so far from a broader perspective. This review brings a different thinking to researchers, with the neglected features and potentials of ROS, to relate their works with ROS and to explore the mechanisms between their subject and ROS.

中文翻译：

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ROS和疾病：在新陈代谢和能量供应中的作用。

致力于活性氧（ROS）的研究已经进行了数十年，但结果仍存在争议。经过不懈的研究，研究人员探索了ROS在生物系统和各种疾病中的作用。ROS对于以信号分子形式存在并增强免疫防御的生物系统是有益的。但是，它们也具有有害作用，例如引起组织和器官损伤。在针对ROS和ROS相关疾病的研究中，通过用抑制剂或促进剂调节ROS来研究结果存在争议。这些竞争结果阻碍了进一步调查背后的具体机制的过程。这篇评论中提出的观点从不同的角度解释了ROS的研究，这可能从更广阔的角度解释了迄今为止引入的ROS的竞争结果。