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Scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia: a case report and review of the literature.
Journal of Medical Case Reports ( IF 0.9 ) Pub Date : 2019-12-07 , DOI: 10.1186/s13256-019-2299-x
Weijia Li 1 , Lei Huang 1 , Weixing Zhang 1
Affiliation  

BACKGROUND Scrub typhus is an acute infectious zoonotic disease caused by Orientia tsutsugamushi. Multi-organ dysfunction secondary to scrub typhus is hard to diagnose and has a high mortality rate. Only one case of scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia has been reported thus far. In this study, we report a second case of scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia, and we summarize its diagnosis and treatment. CASE PRESENTATION A 43-year-old Han Chinese woman, a sanitation worker, was admitted to our hospital after 7 days of a skin infection and 5 days of a sore throat with fever and dizziness. A physical examination revealed the presence of an eschar on the right side of her neck. She had a history of insect bites during her sanitation work. A diagnostic evaluation identified scrub typhus as the primary illness, which was associated with multi-organ dysfunction syndrome and immune thrombocytopenia. She recovered completely after 15 days of treatment and extensive symptomatic supportive care. CONCLUSION We report a second case of tsutsugamushi disease with multi-organ dysfunction syndrome and immune thrombocytopenia, which resolved after treatment and extensive care.

中文翻译:

擦洗斑疹伤寒并伴有多器官功能障碍综合征和免疫性血小板减少症:一例病例报告并文献复习。

背景技术斑疹伤寒是由tsu虫东方虫(Orientia tsutsugamushi)引起的一种急性传染性人畜共患病。继发于斑疹伤寒的多器官功能障碍难以诊断,死亡率高。迄今为止,仅报道了一种带多器官功能障碍综合征和免疫性血小板减少症的灌木斑疹伤寒病例。在这项研究中,我们报告了第二例患有多器官功能障碍综合征和免疫性血小板减少症的灌木斑疹伤寒,并总结了其诊断和治疗方法。病例介绍一名43岁的汉族妇女,是一名环卫工人,在皮肤感染7天和喉咙痛伴发烧和头晕的7天后入院。体格检查发现她的脖子右侧有一个焦char。在环卫工作期间,她有被昆虫叮咬的历史。诊断评估确定斑疹伤寒为主要疾病,与多器官功能障碍综合症和免疫性血小板减少症有关。治疗15天和广泛的症状支持治疗后,她完全康复。结论我们报告了另一例多器官功能不全综合征和免疫性血小板减少症的虫病,该病经治疗和广泛护理后得以解决。
更新日期:2019-12-07
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