In the past five years, the surrounding of the brain, that is the meninges (singular meninx) have evolved from being a physical barrier that protects the brain parenchyma to becoming a central player for both the maintenance of normal brain function and the modulation of neurological disorders. Indeed, the meninges are an immunologically active compartment that communicates with the periphery via the (re)discovered meningeal lymphatic system. From its ties to both the periphery and the central nervous system, the meninges are becoming a prevalent organ to understand and modulate brain homeostasis. Here we will focus on current advances in our understanding of the meningeal compartment with an emphasis on the meningeal lymphatic network as a key regulator.

中文翻译：

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脑膜淋巴瘤，免疫力和神经炎症。

在过去的五年中，脑部周围的环境，即脑膜（单一的脑膜）已经从保护大脑实质的物理屏障发展成为维持正常脑功能和调节神经系统的中心参与者。失调。实际上，脑膜是一种免疫学活性的区室，其通过（重新）发现的脑膜淋巴系统与周围区域连通。从与周围神经系统和中枢神经系统的联系开始，脑膜正逐渐成为理解和调节脑稳态的主要器官。在这里，我们将重点关注对脑膜区室的最新进展，重点是脑膜淋巴管网作为关键调节因子。