Recreating, expanding and using nephron progenitor populations.,Nature Reviews Nephrology

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Recreating, expanding and using nephron progenitor populations.
Nature Reviews Nephrology ( IF 28.6 ) Pub Date : 2020-02-01 , DOI: 10.1038/s41581-019-0238-0
Melissa H Little _{1,

2,

3} , Kynan T Lawlor ₁

Affiliation

2019 saw advances in the generation of induced pluripotent stem cell (iPSC)-derived nephron progenitors and in our understanding of how nephrons form in a kidney organoid. Fundamental studies of regeneration in zebrafish continue to provide vital clues as to how we might use iPSC-derived cells to regenerate a human nephron in vivo.

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