A recent article by Sung et al. identified the CLEC2 platelet receptor as an important factor of lethal dengue virus infection. Formation of neutrophil extracellular traps via crosstalk with CLEC5A and TLR2 neutrophils were ascribed a causative role in DENV infection. This provides new insights for the development of candidate broad-spectrum therapies against hemorrhagic virus infections.

中文翻译：

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登革热病毒感染过程中嗜中性粒细胞胞外诱捕物的有害作用。

Sung等人的最新文章。已确定CLEC2血小板受体是致死登革热病毒感染的重要因素。通过与CLEC5A和TLR2中性粒细胞的串扰形成中性粒细胞外陷阱的原因是DENV感染。这为开发针对出血性病毒感染的广谱疗法提供了新的见识。