Metabolism has emerged as a key player for stem cell behavior; however, the role of metabolism in the microenvironment remains poorly understood. In this issue of Cell Stem Cell, Wang et al. (2019) show that brain endothelial cells directly affect adult neural stem cells and maintain a healthy metabolic environment by regulating lactate levels.

中文翻译：

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感知环境：细胞外乳酸水平控制成人神经发生。

代谢已成为干细胞行为的关键因素。然而，关于代谢在微环境中的作用仍然知之甚少。在本期《细胞干细胞》中，Wang等人。（2019）显示脑内皮细胞直接影响成年神经干细胞并通过调节乳酸水平来维持健康的代谢环境。