当前位置: X-MOL 学术Mol. Cell › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Watch Out for Those Terrible Twos! Dinucleotide Accumulation Dysregulates Mitochondrial Transcription.
Molecular Cell ( IF 16.0 ) Pub Date : 2019-12-05 , DOI: 10.1016/j.molcel.2019.11.002
Melvin Noe Gonzalez 1 , Jesper Q Svejstrup 1
Affiliation  

In this issue of Molecular Cell, Nicholls et al. (2019) show that the oligoribonuclease REXO2 degrades mitochondrial RNA dinucleotides to prevent RNA-primed transcription at non-canonical sites in the mitochondrial genome, shedding new light on the importance of complete RNA degradation for transcriptional integrity.

中文翻译:

当心那些可怕的二人!二核苷酸积累失调线粒体转录。

在本期《分子细胞》中,Nicholls等人。(2019)显示寡核糖核酸酶REXO2降解线粒体RNA二核苷酸,以防止线粒体基因组中非规范位点的RNA引发的转录,这为完全降解RNA对转录完整性的重要性提供了新的思路。
更新日期:2019-12-05
down
wechat
bug