Gastrointestinal (GI) diseases are often associated with hypertrophy of the layers of the GI wall, along with dilatation and a denervation of smooth muscle cells which alters the biomechanical properties of the tissue. ‘Balloon distension’ is a specialised experimental protocol performed on hollow organs to investigate their biomechanical properties. A balloon is inserted and pressurized during this procedure and the change in external diameter is monitored as a function of the applied pressure. A hyperelastic framework is often used in this context to evaluate the stresses in the wall after inflation. However, this only gives an idea about the final equilibrium state of the tissue, whereas the intermediate states of deformations are overlooked. GI soft tissues are viscoelastic, thus, the stress values during inflation are loading rate dependent and are higher than the equilibrium state values. Therefore, it is necessary to consider the time- and rate-dependent material properties during a balloon distension test. The aim of this work was to develop a viscoelastic framework for interpreting balloon distension experiments under finite deformation. To demonstrate the efficacy of the framework, it was used to recreate experimental results from intestinal and colonic tissue segments. In all cases, the simulation results were well matched ($R^2>0.9$) with the experimental data.

胃肠道（GI）疾病通常与GI壁各层肥大，平滑肌细胞的扩张和神经支配失调有关，从而改变了组织的生物力学特性。“气球膨胀”是在中空器官上进行的专门实验方案，旨在研究其生物力学特性。在此过程中，将球囊插入并加压，并根据施加的压力监控外径的变化。在这种情况下，通常使用超弹性框架来评估充气后墙体中的应力。然而，这仅给出关于组织的最终平衡状态的想法，而忽略变形的中间状态。胃肠道软组织是粘弹性的，因此，充气期间的应力值取决于加载速率，并且高于平衡状态值。因此，有必要在球囊膨胀测试中考虑时间和速率相关的材料特性。这项工作的目的是开发一种粘弹性框架，用于解释有限变形下的球囊扩张实验。为了证明该框架的有效性，将其用于从肠和结肠组织段中重建实验结果。在所有情况下，仿真结果均匹配良好（这项工作的目的是开发一种粘弹性框架，用于解释有限变形下的球囊扩张实验。为了证明该框架的有效性，将其用于从肠和结肠组织段中重建实验结果。在所有情况下，仿真结果均匹配良好（这项工作的目的是开发一个粘弹性框架，用于解释有限变形下的球囊扩张实验。为了证明该框架的有效性，将其用于从肠和结肠组织段中重建实验结果。在所有情况下，仿真结果均匹配良好（${\mathrm{[R}}^{\mathrm{2个}}>0.9$）与实验数据。