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Acute onset binocular diplopia: a retrospective observational study of 100 consecutive cases managed at a tertiary eye centre in Saudi Arabia
Eye ( IF 2.8 ) Pub Date : 2019-12-04 , DOI: 10.1038/s41433-019-0705-7 Sunil Kumar 1
Eye ( IF 2.8 ) Pub Date : 2019-12-04 , DOI: 10.1038/s41433-019-0705-7 Sunil Kumar 1
Affiliation
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To evaluate the demography, aetiology and clinical course of acute onset binocular diplopia (AOBD) in patients presented as emergency and managed at the neuroophthalmology clinic of a tertiary eye care centre in Saudi Arabia. A retrospective review of the medical records of 100 consecutive patients who attended the emergency department of Dhahran Eye Specialist Hospital with isolated, AOBD. The exclusion criteria were: (a) monocular diplopia, (b) binocular diplopia accompanied with neurological deficits other than ocular muscles dysfunction and (c) thyroid eye disease. All patients were followed until resolution of the diplopia or onward referral to another specialty for further management. Male:female ratio was 2:1. Median age of the cohort was 56 years (range 18–90 years). Associated nerve palsy included: abducens nerve (n = 57 patients), oculomotor (n = 32 patients) and trochlear nerve (n = 3 patients). Microvascular ischaemia and ocular myasthenia gravis were two most common pathogenic mechanisms. AOBD resolved spontaneously in 98% of patients. AOBD, though an alarming and distressing condition, carries reassuringly good prognosis in majority of patients. High risk factors for vascular disease in Middle-Eastern population are reflected in microvascular aetiology as the major cause.
中文翻译：
急性发作的双眼复视：在沙特阿拉伯三级眼科中心管理的 100 例连续病例的回顾性观察研究
评估在沙特阿拉伯三级眼科护理中心的神经眼科诊所就诊和治疗的急诊患者中急性发作性双眼复视 (AOBD) 的人口学、病因和临床病程。对在 Dhahran 眼科专科医院急诊科就诊的 100 名患有孤立性 AOBD 的连续患者的病历进行回顾性分析。排除标准是：（a）单眼复视，（b）双眼复视伴有除眼肌功能障碍以外的神经功能缺损和（c）甲状腺眼病。对所有患者进行随访，直到复视解决或转诊到另一个专科进行进一步治疗。男女比例为 2:1。队列的中位年龄为 56 岁（范围 18-90 岁）。相关神经麻痹包括：外展神经（n = 57 名患者），动眼神经（n = 32 名患者）和滑车神经（n = 3 名患者）。微血管缺血和眼部重症肌无力是两种最常见的致病机制。98% 的患者 AOBD 自行消退。AOBD 虽然是一种令人担忧和痛苦的疾病，但在大多数患者中预后良好，令人欣慰。中东人群血管疾病的高危因素反映在微血管病因学上是主要原因。
更新日期：2019-12-04
中文翻译：
急性发作的双眼复视：在沙特阿拉伯三级眼科中心管理的 100 例连续病例的回顾性观察研究
评估在沙特阿拉伯三级眼科护理中心的神经眼科诊所就诊和治疗的急诊患者中急性发作性双眼复视 (AOBD) 的人口学、病因和临床病程。对在 Dhahran 眼科专科医院急诊科就诊的 100 名患有孤立性 AOBD 的连续患者的病历进行回顾性分析。排除标准是：（a）单眼复视，（b）双眼复视伴有除眼肌功能障碍以外的神经功能缺损和（c）甲状腺眼病。对所有患者进行随访，直到复视解决或转诊到另一个专科进行进一步治疗。男女比例为 2:1。队列的中位年龄为 56 岁（范围 18-90 岁）。相关神经麻痹包括：外展神经（n = 57 名患者），动眼神经（n = 32 名患者）和滑车神经（n = 3 名患者）。微血管缺血和眼部重症肌无力是两种最常见的致病机制。98% 的患者 AOBD 自行消退。AOBD 虽然是一种令人担忧和痛苦的疾病，但在大多数患者中预后良好，令人欣慰。中东人群血管疾病的高危因素反映在微血管病因学上是主要原因。
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