The considerable performance enhancement of small molecule‐sieving nanofiltration membrane has been achieved by the functional combination between host–guest chemistry and interfacial polymerization (IP) for the first time in this work. First, the water‐insolubility of cucurbit[6]uril (CB6) was ameliorated by constructing host–guest complex (CB6‐PIP) with piperazine. Second, the incorporation of water‐soluble CB6‐PIP in the selective layer via IP leads to the generation of not only the enlarged conventional polyamide network tunnels but also rotaxane tunnels. Such enrichment of solvent transport tunnels contributes to an amazing pure water permeability of 15.5–25.4 Lm⁻²bar⁻¹h⁻¹, three times higher than that of traditional polyamide membranes, with a high R/MgSO₄ of 99.5–92.5%, perfect SO₄²⁻/Cl⁻ selectivity due to the electronegative contribution of CB6, as well as untapped potential in organic solvent nanofiltration. This work not only provides a fire‐new strategy to design new type of NF materials but also promotes the application of CBs in many other fields.

中文翻译：

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基于葫芦素的主客体化学对聚酰胺纳米过滤膜的令人鼓舞的改进

这项工作中，主体-客体化学和界面聚合（IP）之间的功能结合首次实现了小分子筛分纳滤膜的显着性能提升。首先，通过用哌嗪构建宿主-客体复合物（CB6-PIP），改善了葫芦[6] uril（CB6）的水不溶性。其次，通过IP将水溶性CB6-PIP掺入选择层不仅导致产生扩大的常规聚酰胺网络隧道，而且导致产生轮烷烷烃隧道。溶剂传输通道的这种富集有助于实现令人惊讶的15.5–25.4 Lm ^-2 bar ^-1 h ^-1的纯水渗透率，比传统的聚酰胺膜的高三倍，具有高R /硫酸镁₄的99.5-92.5％，完善SO ₄ ^{2- /}氯^-选择性由于CB6的电负性的贡献，以及在有机溶剂中纳滤尚未开发的潜力。这项工作不仅为设计新型的NF材料提供了崭新的策略，而且还促进了CB在许多其他领域的应用。