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Organization of Chromosomal DNA by SMC Complexes.
Annual Review of Genetics ( IF 8.7 ) Pub Date : 2019-12-03 , DOI: 10.1146/annurev-genet-112618-043633
Stanislau Yatskevich 1 , James Rhodes 2 , Kim Nasmyth 2
Affiliation  

Structural maintenance of chromosomes (SMC) complexes are key organizers of chromosome architecture in all kingdoms of life. Despite seemingly divergent functions, such as chromosome segregation, chromosome maintenance, sister chromatid cohesion, and mitotic chromosome compaction, it appears that these complexes function via highly conserved mechanisms and that they represent a novel class of DNA translocases.

中文翻译:


SMC 复合物对染色体 DNA 的组织。



染色体结构维持 (SMC) 复合体是所有生命领域染色体结构的关键组织者。尽管看似不同的功能,例如染色体分离、染色体维持、姐妹染色单体凝聚和有丝分裂染色体压缩,但这些复合物似乎通过高度保守的机制发挥作用,并且它们代表了一类新型的 DNA 易位酶。
更新日期:2020-04-21
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