Cathepsin D is a ubiquitous lysosomal protease that is primarily secreted due to oxidative stress. The role of circulating cathepsin D in heart failure (HF) is unknown. The aim of this study is to determine the association between circulating cathepsin D levels and clinical outcomes in patients with HF and to investigate the biological settings that induce the release of cathepsin D in HF.

中文翻译：

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组织蛋白酶D在心力衰竭的病理生理中的作用及其潜在的有益特性：一种翻译方法。

组织蛋白酶D是一种普遍存在的溶酶体蛋白酶，主要由于氧化应激而分泌。循环组织蛋白酶D在心力衰竭（HF）中的作用尚不清楚。这项研究的目的是确定循环组织蛋白酶D水平与HF患者的临床结局之间的关系，并研究诱导组织蛋白酶D在HF中释放的生物学环境。