Over the past decade, our understanding of intestinal immunology has been transformed by the realization that the gut microbiota shapes immune development, function and disease susceptibility. Strikingly, the enteric nervous system is now emerging as a cellular hub that sense microbiota-derived signals and rapidly orchestrate immunological outcomes. Here, I discuss recent advances in our understanding of intestinal neuroimmune communications, their modulation by the gut microbiota, and the consequent impact on host immunity, in health and disease.

中文翻译：

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Ménageàtrois：通过肠道神经免疫微生物群交调来调节宿主的免疫力。

在过去的十年中，人们对肠道微生物群影响免疫发育，功能和疾病易感性的认识，已经改变了我们对肠道免疫学的理解。令人惊讶的是，肠神经系统现在已成为一种细胞枢纽，可感知微生物群衍生的信号并快速协调免疫结果。在这里，我讨论了肠道神经免疫通讯，肠道微生物群对肠道神经免疫通讯的调控及其对宿主免疫力（健康和疾病）的影响等方面的最新进展。