The production of glucuronic acid via enzyme catalysis from biomass is slow. Here we studied the oxidation of methoxy-protected glucose (MG) using Pd-on-Au nanoparticle model catalysts to generate methoxy-protected glucuronic acid (MGA), a precursor to glucuronic acid. Pd-on-Au showed volcano-shape activity dependence on calculated Pd surface coverage (sc). The 80 sc% Pd-on-Au catalyst composition showed maximum initial turnover frequency (413 mol-MG mol-surface-atom⁻¹ h⁻¹) that was 5× higher than that of Au/C, while Pd/C was inactive. This Pd-on-Au composition gave the highest MGA yield (46%), supporting a bimetallic approach to glucuronic acid production.

通过酶催化从生物质中生产葡萄糖醛酸的速度很慢。在这里，我们研究了使用Au-Pd纳米颗粒模型催化剂对甲氧基保护的葡萄糖（MG）进行氧化，以生成甲氧基保护的葡萄糖醛酸（MGA），即葡萄糖醛酸的前体。Au上的Pd表现出火山形活动对计算出的Pd表面覆盖率（sc）的依赖性。80 sc％的Pd-on-Au催化剂组合物显示出最大的初始周转频率（413 mol-MG mol-表面原子^-1  h ^-1），比Au / C高出5倍，而Pd / C处于非活性状态。这种Pd-on-Au组合物的MGA产率最高（46％），支持了双金属方法生产葡萄糖醛酸。