Remyelination declines in the aging central nervous system due to oligodendrocyte precursor cell (OPC) dysfunction. In the latest issue of Cell Stem Cell, Neumann et al. (2019) demonstrate that aged OPCs are amenable to functional rejuvenation by systemic interventions involving alternate-day fasting or treatment with the fasting mimetic metformin.

中文翻译：

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饮食中的OPC：年轻时的髓鞘再生服务。

由于少突胶质前体细胞（OPC）功能障碍，中枢神经系统的衰老过程中髓鞘再生减少。在最新一期的《细胞干细胞》中，Neumann等人。（2019）证明了老年OPC可以通过隔天禁食或用禁食模拟二甲双胍治疗的系统干预来恢复功能。