Deciphering immunity at high plexity and resolution.,Nature Reviews Immunology

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Deciphering immunity at high plexity and resolution.
Nature Reviews Immunology ( IF 67.7 ) Pub Date : 2020-02-01 , DOI: 10.1038/s41577-019-0254-0
Cecilia Domínguez Conde ₁ , Sarah A Teichmann _{1,

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Affiliation

The power of single-cell genomics stems from the ability to explore cell types and cell states in an unbiased way, which can lead to surprising new insights relating to developmental changes, tissue architecture and disease mechanisms. 2019 has yielded an exceptional number of high-quality, single-cell studies of the immune system in development, homeostasis and disease. Here, we highlight a selection of these. Single-cell sequencing studies in 2019 have led to exciting discoveries relevant to the roles of the immune system in development, homeostasis and disease.

中文翻译：

在高复杂度和分辨率下解密免疫。

单细胞基因组学的力量源于以一种无偏见的方式探索细胞类型和细胞状态的能力，这可以导致与发育变化，组织结构和疾病机制有关的令人惊讶的新见解。2019年，有关发育，体内平衡和疾病免疫系统的高质量，单细胞研究获得了数量惊人的成果。在这里，我们重点介绍这些内容。2019年的单细胞测序研究导致了令人兴奋的发现，这些发现与免疫系统在发育，体内平衡和疾病中的作用有关。

更新日期：2019-12-04

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