The particular combinations of alleles that define haplotypes along individual chromosomes can be determined with increasing ease and accuracy by using current sequencing technologies. Beyond allele frequencies, haplotype data collected in population samples contain information about the history of allelic associations in gene genealogies, and this is of tremendous potential for conservation genomics. We provide an overview of how haplotype information can be used to assess historical demography, gene flow, selection, and the evolutionary outcomes of hybridization across different timescales relevant to conservation issues. We address technical aspects of applying such approaches to nonmodel species. We conclude that there is much to be gained by integrating haplotype-based analyses in future conservation genomics studies.

中文翻译：

---

使用单倍型信息进行保护基因组学研究。

可以使用当前的测序技术，以越来越容易和准确的方式确定沿单个染色体定义单倍型的等位基因的特定组合。除等位基因频率外，人群样本中收集的单倍型数据还包含有关基因谱系中等位基因关联的历史信息，这对于保存基因组学具有巨大的潜力。我们提供了有关如何使用单倍型信息评估历史人口统计学，基因流，选择以及与保护问题相关的不同时间范围内杂交进化结果的概述。我们解决将此类方法应用于非模型物种的技术方面。我们得出结论，将基于单倍型的分析整合到未来的保护基因组学研究中将会获得很多收获。