We report the efficiency of green subcritical water extraction (SWE) for the recovery of bioactive compounds from Allium hookeri root (AHR). The highest extraction yield (88 wt%) and highest contents of bioactive compounds including total phenolic content (29.4 mg of gallic acid equivalent/g of dry AHR), total flavonoid content (30.6 mg of quercetin equivalent/g of dry AHR), ascorbic acid (81 mg/g of dry AHR), and gallic acid (2.8 mg/g of dry AHR), as well as high concentrations of Maillard reaction products (melanoidins), and various rare sugars were achieved at 160 °C for 30 min. The SWE extracts possessed 89.3–91.8 % higher antioxidant activities than those of the Soxhlet water extract. As a result, the SWE extract showed strong anticancer effects against human cancer cells of the HT-1080 (fibrosarcoma) and MDA-MB-231 (breast cancer) cell lines, suggesting the possible application of the AHR extract obtained via SWE in cancer therapy and prevention.

我们报告绿色次临界水提取（SWE）从葱属钩虫中回收生物活性化合物的效率根（AHR）。最高的提取率（88 wt％）和最高的生物活性化合物含量，包括总酚含量（29.4 mg没食子酸当量/ g干燥AHR），总类黄酮含量（30.6 mg槲皮素当量/ g干燥AHR），抗坏血酸酸（81毫克/克干AHR）和没食子酸（2.8毫克/克干AHR），以及高浓度的美拉德反应产物（类黑素）和各种稀有糖在160°C的条件下保持30分钟。SWE提取物的抗氧化活性比索氏提取物高89.3–91.8％。结果，SWE提取物对HT-1080（纤维肉瘤）和MDA-MB-231（乳腺癌）细胞系的人癌细胞显示出强大的抗癌作用，这表明通过AWE提取物获得的AHR提取物有可能应用 SWE在癌症的治疗和预防中。