We report a series of efficient procedures to prepare 2-nitrophenyl-4-aryl-1,2,3-triazoles avoiding the isolation of potentially hazardous 2-nitrophenyl azides. An organocatalyzed azide-enolate variant allows efficient access to the target compounds while it was shown that a metal-catalyzed azide-alkyne procedure involving a preliminary ­Sonogashira coupling was feasible starting from electron-deficient aryl iodides.

中文翻译：

---

不分离 2-硝基苯基叠氮化物合成 2-硝基苯基-4-芳基-1,2,3-三唑的点击变化

我们报告了一系列制备 2-硝基苯基-4-芳基-1,2,3-三唑的有效程序，避免了潜在危险的 2-硝基苯基叠氮化物的分离。有机催化的叠氮化物-烯醇变体可以有效地获取目标化合物，同时表明，从缺电子的芳基碘化物开始，涉及初步 Sonogashira 偶联的金属催化的叠氮化物-炔烃程序是可行的。