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Regulatory Factor X 7 and its Potential Link to Lymphoid Cancers.
Trends in Cancer ( IF 14.3 ) Pub Date : 2019-12-03 , DOI: 10.1016/j.trecan.2019.11.001
Berenice A Fischer 1 , Sonia T Chelbi 1 , Greta Guarda 1
Affiliation  

Alterations in the Regulatory factor X 7 (RFX7) gene have recurrently been reported in lymphoid cancers. Uncharacterized until recently, this transcription factor regulates genes important for ciliogenesis and for limiting cellular metabolic activity. Here we discuss these observations and conjecture on the links between the reported functions of RFX7 and its potential role in lymphoid cancers, encouraging future studies in these directions.



中文翻译:

调节因子X 7及其与淋巴癌的潜在联系。

淋巴癌中反复报道了调节因子X 7RFX7)基因的改变。直到最近,该转录因子仍未表征,它调节对于纤毛发生和限制细胞代谢活性重要的基因。在这里,我们讨论了这些观察结果,并推测了RFX7的报道功能与其在淋巴样癌中的潜在作用之间的联系,并鼓励了这些方向的进一步研究。

更新日期:2019-12-03
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