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LDAF1 Holds the Key to Seipin Function.
Developmental Cell ( IF 10.7 ) Pub Date : 2019-12-02 , DOI: 10.1016/j.devcel.2019.11.009 Joel M Goodman 1
Developmental Cell ( IF 10.7 ) Pub Date : 2019-12-02 , DOI: 10.1016/j.devcel.2019.11.009 Joel M Goodman 1
Affiliation
Seipin is an ER protein important for the assembly of cytoplasmic lipid droplets. In this issue of Developmental Cell, Chung et al. (2019) show that a stable seipin-binding protein, LDAF1/promethin, functions with seipin by attracting triacylglycerol and then allowing this lipid to accumulate and partition into nascent droplets.
中文翻译:
LDAF1按住Seipin功能键。
Seipin是一种ER蛋白,对于细胞质脂质小滴的组装非常重要。在本期《发育细胞》中,Chung等人。(2019)表明,稳定的seipin结合蛋白LDAF1 / promethin通过吸引三酰基甘油,然后使这种脂质积累并分配成新生的液滴,与seipin一起发挥作用。
更新日期:2019-12-02
中文翻译:
LDAF1按住Seipin功能键。
Seipin是一种ER蛋白,对于细胞质脂质小滴的组装非常重要。在本期《发育细胞》中,Chung等人。(2019)表明,稳定的seipin结合蛋白LDAF1 / promethin通过吸引三酰基甘油,然后使这种脂质积累并分配成新生的液滴,与seipin一起发挥作用。