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T-box RNA gets boxed.
Nature Structural & Molecular Biology ( IF 12.5 ) Pub Date : 2019-12-01 , DOI: 10.1038/s41594-019-0340-9
Jacob W Weaver 1 , Alexander Serganov 1
Affiliation  

Bacterial T-boxes are regulatory mRNA regions that control the transcription or translation of factors involved in amino acid supply. T-boxes act by directly binding to non-aminoacylated tRNA in response to amino acid starvation. Three studies now capture three-dimensional structures of tRNA–T-box complexes and reveal a set of RNA features that are required for the recognition of specific tRNAs and modulation of gene expression.

中文翻译:

T-box RNA 被装箱。

细菌 T-box 是调节 mRNA 区域,控制参与氨基酸供应的因子的转录或翻译。T-box 通过直接结合非氨酰化 tRNA 来响应氨基酸饥饿而发挥作用。现在,三项研究捕获了 tRNA-T-box 复合物的三维结构,并揭示了识别特定 tRNA 和调节基因表达所需的一组 RNA 特征。
更新日期:2019-12-02
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