Abstract An improved method was developed for determining highly toxic 2,3,7,8-substituted polychlorinated dibenzo-p-dioxins and polychlorinated dibenzo-p-furans (PCDD/Fs) in sanitary napkins. Samples were extracted by Soxhlet (50% dichloromethane/hexane) and sonication (hexane), and a multi-layer silica column was used for clean-up after acetone precipitation to separate the superabsorbent polymers. Improved separation efficiency of PCDD/Fs from sanitary napkins with a high level of superabsorbent polymers was achieved using the acetone precipitation method. Hexane was then applied as an alternative solvent to remove residual interfering substances including sticky components contained on sanitary napkins via alumina column chromatography in the second clean-up step. Recoveries approached 100% with an average relative standard deviation of less than 15%, and recoveries of internal standards were from 70.5 to 114.8% and 0.6 to 13.6% for the two extraction methods. The mean method detection limit was 0.075–0.968 pg/g for Soxhlet extraction and 0.0032–0.091 pg/g for sonication extraction. The established method meets the quality criteria for the screening of dioxins stated in EU Regulations 589/2014 and 709/2014, and therefore provides a suitable alternative for the determination of dioxins in sanitary napkins containing superabsorbent polymers.

中文翻译：

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测定卫生巾中多氯二苯并对二恶英和二苯并呋喃 (PCDD/Fs) 的改进方法

摘要 建立了测定卫生巾中剧毒2,3,7,8-取代多氯二苯并对二恶英和多氯二苯并对呋喃(PCDD/Fs)的改进方法。样品通过索氏提取（50% 二氯甲烷/己烷）和超声（己烷）提取，丙酮沉淀后使用多层硅胶柱进行净化，以分离高吸水性聚合物。使用丙酮沉淀法提高了卫生巾中 PCDD/Fs 与高吸水性聚合物的分离效率。然后使用己烷作为替代溶剂，在第二个净化步骤中通过氧化铝柱色谱去除残留的干扰物质，包括卫生巾上含有的粘性成分。回收率接近 100%，平均相对标准偏差小于 15%，两种提取方法的内标回收率分别为 70.5% 至 114.8% 和 0.6% 至 13.6%。索氏提取的平均方法检测限为 0.075–0.968 pg/g，超声提取的平均方法检测限为 0.0032–0.091 pg/g。所建立的方法符合欧盟法规 589/2014 和 709/2014 中规定的二恶英筛查质量标准，因此为测定含有高吸水性聚合物的卫生巾中的二恶英提供了合适的替代方案。