Process Optimization, Product Profile Mapping, and Intensification of 1,1-Diamino-2,2-dinitroethylene,Organic Process Research & Development

当前位置： X-MOL 学术 › Org. Process Res. Dev. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Process Optimization, Product Profile Mapping, and Intensification of 1,1-Diamino-2,2-dinitroethylene
Organic Process Research & Development ( IF 3.1 ) Pub Date : 2019-12-16 , DOI: 10.1021/acs.oprd.9b00372
Pandurang M. Jadhav _{1,

2} , Radhakrishnan Sarangapani ₁ , Rajendra S. Patil ₃ , Raj K. Pandey ₁

Affiliation

Industrialization of a chemical process needs an understanding of process chemistry, optimal process envelope, and the best choice of operation. 1,1-Diamino-2,2-dinitroethylene (FOX-7) is a new generation, and the highly insensitive compound finds application in high-energy formulations as well as preparation of novel high-energy compounds. The present study highlights efforts made for establishing a continuous process for FOX-7. The intermediates of nitration of 2-methylpyrimidine-4, 6-dione were isolated and characterized by spectroscopic tools. Reaction kinetics was also derived for the formation of intermediates. Product profiles of the reaction were evaluated on deriving expressions for various reactors. The simultaneous effect of heat and reaction was evaluated in a tubular reactor to obtain the runaway reaction condition. The effective reactor scheme was evaluated, designed, and experimented. Process intensification was carried out in a continuous set up comprising various contact patterns. The present study delivered a safe and productive method for FOX-7 processing

中文翻译：

工艺优化，产品概况图和1,1-二氨基-2,2-二硝基乙烯的强化

化学过程的工业化需要对过程化学，最佳过程范围和最佳操作选择的理解。1,1-二氨基-2,2-二硝基乙烯（FOX-7）是新一代产品，这种高度不敏感的化合物可用于高能制剂以及新型高能化合物的制备中。本研究强调了为建立FOX-7的连续过程而做出的努力。分离了2-甲基嘧啶-4、6-二酮的硝化中间体，并用光谱仪器对其进行了表征。还推导了反应动力学以形成中间体。根据各种反应器的推导表达式评估反应的产物概况。在管式反应器中评估热和反应的同时作用，以获得失控的反应条件。对有效的反应堆方案进行了评估，设计和试验。在包括各种接触模式的连续设置中进行工艺强化。本研究为FOX-7的加工提供了一种安全有效的方法

更新日期：2019-12-17

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11