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Detection of severe hypertension in a patient with neurofibromatosis type 1 during anesthesia induction: a case report.
Journal of Medical Case Reports ( IF 0.9 ) Pub Date : 2019-11-30 , DOI: 10.1186/s13256-019-2292-4
Juan Wang 1 , Guohua Wei 1 , Zhongyun Wang 1 , He Huang 1
Affiliation  

BACKGROUND Neurofibromatosis type 1 has a higher prevalence of pheochromocytoma and paraganglioma than the general population: 1.0-5.7% versus 0.2-0.6%. Currently, there are no generally accepted guidelines for screening for pheochromocytoma and paragangliomas in asymptomatic patients with neurofibromatosis type 1. CASE PRESENTATION Severe hypertension developed during anesthesia induction in our patient, a 44-year-old Chinese man with neurofibromatosis type 1. We screened for catecholamine level after glioma resection, and the patient was diagnosed with combined pheochromocytoma and paraganglioma. CONCLUSIONS A delay in diagnosis or lack of a diagnosis in pheochromocytoma and paraganglioma may increase the perioperative morbidity and mortality risk due to excess catecholamine secretion. Therefore, routine pheochromocytoma and paraganglioma screening preoperatively in patients with neurofibromatosis type 1 is very important.

中文翻译:

麻醉诱导期间1型神经纤维瘤病患者的严重高血压检测:一例报告。

背景技术1型神经纤维瘤病的嗜铬细胞瘤和副神经节瘤患病率高于一般人群:1.0-5.7%对0.2-0.6%。目前,尚无公认的筛查1型无症状神经纤维瘤病患者嗜铬细胞瘤和副神经节瘤的指南。脑胶质瘤切除后儿茶酚胺水平升高,并且该患者被诊断为合并嗜铬细胞瘤和副神经节瘤。结论嗜铬细胞瘤和副神经节瘤的诊断延迟或缺乏诊断可能会由于儿茶酚胺分泌过多而增加围手术期的发病率和死亡风险。所以,
更新日期:2019-11-30
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