OBJECTIVE To examine the association between individual-level deprivation and health-related quality of life (HRQL) in the general population. METHODS Data from a population-based survey in the Canadian province of Alberta were used. Individual-level deprivation was assessed using the Canadian Deprivation Index (CDI) and the Ontario Deprivation Index (ODI). HRQL was assessed using the EQ-5D-5 L. Differences in problems in the EQ-5D-5 L dimensions, index and visual analogue scale (VAS) scores across levels of deprivation were examined. Multivariate logistic and linear regression models adjusted for socio-demographic and other characteristics were used to examine the independent association between deprivation and HRQL. RESULTS Of the 6314 respondents, 39% were aged between 18 and 44 years and 38% between 45 and 64 years; 60% were female. Mean EQ-5D-5 L index and VAS scores were 0.85 (standard deviation [SD] 0.14) and 79.6 (SD 17.7), respectively. Almost one-third (30.6%) of respondents reported no problems on all EQ-5D-5 L dimensions. Few participants reported some problems with mobility (23.8%), self-care (6.2%) and usual activities (25.2%), while 59.3 and 35.5% reported some levels of pain/discomfort and anxiety/depression, respectively. Differences between the most and least deprived in reporting problems in EQ-5D-5 L dimensions, index and VAS scores were statistically significant and clinically important. In adjusted regression models for both deprivation indices, the least well-off, compared to the most well-off, had higher likelihood of reporting problems in all EQ-5D-5 L dimensions. Compared to the most well-off, the least well-off had an EQ-5D-5 L index score decrement of 0.18 (p < 0.01) and 0.17 (p < 0.01) for the CDI and ODI, respectively. Similarly, an inverse association was found between the VAS score and the CDI (β = - 17.3, p < 0.01) as well as the ODI (β = - 13.3, p < 0.01). CONCLUSION Individual-level deprivation is associated with worse HRQL. Poverty reduction strategies should consider the effects of not only neighbourhood-level deprivation, but also that of individual-level deprivation to improve overall health.

中文翻译：

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个人层面的剥夺与健康相关的生活质量之间的关系。

目的探讨普通人群中个人剥夺与健康相关的生活质量（HRQL）之间的关系。方法使用加拿大艾伯塔省基于人口的调查数据。使用加拿大剥夺指数（CDI）和安大略剥夺指数（ODI）评估个人级别的剥夺。使用EQ-5D-5 L评估了HRQL。检查了EQ-5D-5 L尺寸，指数和视觉模拟量表（VAS）得分在整个剥夺水平上的问题差异。根据社会人口统计学和其他特征调整的多元逻辑和线性回归模型用于检验剥夺与HRQL之间的独立关联。结果6314名受访者中，年龄在18至44岁之间的占39％，年龄在45至64岁之间的占38％。60％是女性。平均EQ-5D-5 L指数和VAS评分分别为0.85（标准差[SD] 0.14）和79.6（SD 17.7）。几乎三分之一（30.6％）的受访者表示在所有EQ-5D-5 L尺寸上均没有问题。很少有参与者报告出一些行动不便（23.8％），自我保健（6.2％）和日常活动（25.2％）的问题，而59.3和35.5％的人分别报告了一定程度的疼痛/不适和焦虑/抑郁。EQ-5D-5 L尺寸，指数和VAS分数在报告问题中被剥夺最多和最少的差异具有统计学意义，并在临床上具有重要意义。在针对两个贫困指数的调整回归模型中，与最富裕的人群相比，最富裕的人群在所有EQ-5D-5 L维度上报告问题的可能性更高。与最富裕的人相比，CDI和ODI的最不富裕者的EQ-5D-5 L指数得分分别下降0.18（p <0.01）和0.17（p <0.01）。同样，在VAS分数与CDI（β=-17.3，p <0.01）和ODI（β=-13.3，p <0.01）之间发现反相关。结论个人层面的剥夺与HRQL恶化有关。减贫战略不仅应考虑社区一级的贫困的影响，而且还应考虑个人一级的贫困的影响，以改善整体健康状况。