While biologic therapies have dramatically improved the management of rheumatoid arthritis (RA), not all patients respond well to treatment and the field continues to await individualized medicine approaches that promise to determine effective medications based on a patient's distinct disease features. The cellular and molecular characterization of an individual's synovium holds promise to understand pathology, predict outcomes and tailor treatment decisions, akin to the histologic and genetic assessment of tumor tissue that guides cancer care.

中文翻译：

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推进类风湿关节炎滑膜活检分析：一次一个 B 细胞。


虽然生物疗法极大地改善了类风湿性关节炎 (RA) 的治疗，但并非所有患者都对治疗反应良好，该领域仍在等待有望根据患者独特疾病特征确定有效药物的个体化医学方法。个体滑膜的细胞和分子特征有望了解病理学、预测结果和定制治疗决策，类似于指导癌症治疗的肿瘤组织的组织学和遗传评估。