Although the association between mutations in GBA1 and parkinsonism is well established, most GBA1 mutation carriers never develop parkinsonism, implicating the contribution of other genetic, epigenetic, and/or environmental modifiers.

中文翻译：

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帕金森氏症戈谢病不一致的同胞对的临床评价

尽管 GBA1 突变与帕金森病之间的关联已经确立，但大多数 GBA1 突变携带者从未发展为帕金森病，这暗示了其他遗传、表观遗传和/或环境修饰因素的作用。