Study design

Retrospective study

Objectives

To describe the epidemiological and clinical profile in a retrospective chart review of individuals with spinal cord injury (SCI) and osteoporosis-related fractures.

Setting

A Brazilian rehabilitation hospital.

Methods

This is a retrospective chart review that included 325 individuals with SCI and osteoporosis-related fractures who were admitted to a Brazilian rehabilitation hospital between January 1997 and December 2017.

Results

Overall, 52% were males with a mean (SD) age of 44.8 (±16.7) years at the time of first fracture. Overall, 82% had paraplegia and 56% had a thoracic neurological level. The mean (SD) time between SCI and fracture was 9.7 (±9.3) years. In 59% of cases the immediate cause of the fracture was a fall. The locations of the fractures were distal femur (27%), proximal femur (27%), and tibia and/or distal fibula (28%). The fractures occurred mostly at home (63%). Complications occurred in 19% of individuals and 25% reported worse performance in activities of daily living and 29% a deterioration in ambulation after they had recovered from the fracture. A second fracture was described in 15% of individuals, and five individuals had a third fracture. The mean (SD) level of 25 hydroxyvitamin D [25 (OH) D] was 25.6 (±15.2) ng/ml, and only 11 individuals (3%) underwent dual energy X-ray absorptiometry (DEXA), and 26 individuals (8%) were treated with antiresorptive drugs after fracture.

Conclusion

Little is done to prevent fractures in individuals with SCI and understanding the clinical and epidemiological profiles will help identify risk factors and establish prevention programs and appropriate treatment.

中文翻译：

---

脊髓损伤后与骨质疏松症相关的骨折：来自巴西的一项回顾性研究。

学习规划

回顾性研究

目标

在回顾性图表回顾中描述患有脊髓损伤（SCI）和骨质疏松症相关骨折的个体的流行病学和临床概况。

环境

巴西康复医院。

方法

这是一项回顾性图表回顾，其中包括325位在1997年1月至2017年12月之间入住巴西康复医院的SCI和骨质疏松相关性骨折的患者。

结果

总体而言，首次骨折时，平均（SD）年龄为44.8（±16.7）岁的男性为52％。总体而言，有82％的患者患有截瘫，而56％的患者具有胸神经功能。SCI和骨折之间的平均（SD）时间为9.7（±9.3）年。在59％的病例中，骨折的直接原因是跌倒。骨折的位置是股骨远端（27％），股骨近端（27％）以及胫骨和/或腓骨远端（28％）。骨折多发生在家庭（63％）。从骨折中恢复后，有19％的人发生并发症，有25％的人在日常生活活动中表现较差，而有29％的患者的活动能力下降。在15％的个体中描述了第二次骨折，其中五个个体发生了第三次骨折。25羟基维生素D [25（OH）D]的平均（SD）水平为25.6（±15.2）ng / ml，

结论

预防SCI个体骨折几乎无济于事，了解临床和流行病学概况将有助于识别危险因素并制定预防计划和适当治疗。