Three new alkaloids (1-3) and a new natural alkaloid (4), named (1′R,3′R,4′R,6′S)-endocycliomurrayamine-A (1), 3-formyle-7-hydroxy-9H-carbazole-1-O-β-d-glucopyranoside (2), 4′-hydroxyphenyl-6-ethyl-1H-pyrrole-2-carboxaldehyde (3), and 4-hydroxyphenoxy-N-methyl-propanamide (4), together with thirteen known alkaloid derivatives (5–17) were isolated from Murraya koenigii. Among them, compounds (8–17) were isolated from this plant for the first time. The structures of compounds (1–17) were elucidated on the basis of their spectroscopic analysis and references. Compounds 1, 15, 16, and 17 (10 μM) showed moderate hepatoprotective activities against d-galactosamine-induced HL-7702 cells damage. Compounds 2, 3, 9, and 13 showed moderate activation of PPARα and PPARγ receptors.

三个新的生物碱（1 - 3）和一个新的天然生物碱（4），命名为（1' R， 3' R， 4' R， 6'小号）-endocycliomurrayamine-A（1），3- formyle -7-羟基-9 H-咔唑-1- O - β - d-吡喃葡萄糖苷（2），4'-羟基苯基-6-乙基-1 H-吡咯-2-羧甲醛（3）和4-羟基苯氧基-N-甲基丙酰胺（4）以及十三种已知的生物碱衍生物（5 – 17）是从Murraya koenigii分离的。其中，化合物（8 – 17）首次从该植物中分离出来。根据其光谱分析和参考，阐明了化合物（1 – 17）的结构。化合物1，15，16，和17（10μM）显示针对中等保肝活动d -galactosamine诱导的HL-7702细胞的损伤。化合物2，3，9，和13显示出PPAR的活化适中α和PPAR γ 受体。