We aimed to investigate the effect of short-term orthokeratology lens or frame glasses wear on corneal thickness, corneal endothelial cells and vision correction in adolescents with low to moderate myopia. Data of 100 adolescents with low to moderate myopia were retrospectively analyzed. The patients were assigned into two groups. The experimental group were treated with night-wear orthokeratology lens, and control group were treated with ordinary frame glasses. Follow up was carried out at the 3rd, 6th and 12th months of treatment. The naked-eye vision, diopter, corneal curvature, intraocular pressure, axial length, endothelial cell count and central corneal thickness were examined. Complications within 12 months were observed, and corneal fluorescein staining was graded. The naked-eye vision of the experimental group was significantly higher than that of the control group at the 3rd, 6th and 12th months, while the diopter of the experimental group was significantly lower than that of the control group at these time points. The corneal curvature of the experimental group was significantly decreased when comparing with that of the control group at the above 3 time points. The increase of axial length in the experimental group was significantly less than that in the control group at the 6th and 12th months. Short-term orthokeratology lens wear can effectively improve the naked-eye vision in adolescents with low to moderate myopia without significant impact on the central corneal thickness and corneal endothelial cells. It is a relatively safe method to correct myopia.

中文翻译：

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短期佩戴角膜塑形镜或普通镜框眼镜对中低度近视青少年的角膜厚度，角膜内皮细胞和视力矫正的影响

我们的目的是调查低度至中度近视青少年短期佩戴角膜塑形镜或镜架眼镜对角膜厚度，角膜内皮细胞和视力矫正的影响。回顾性分析了100名低度至中度近视青少年的数据。将患者分为两组。实验组采用夜用角膜塑形镜治疗，对照组采用普通镜框眼镜治疗。在治疗的第3、6和12个月进行随访。检查了裸眼视力，屈光度，角膜曲率，眼内压，轴向长度，内皮细胞计数和角膜中央厚度。观察到12个月内的并发症，并对角膜荧光素染色进行了分级。在第3、6和12个月，实验组的裸眼视力明显高于对照组，而在这些时间点，实验组的屈光度明显低于对照组。在上述三个时间点，与对照组相比，实验组的角膜曲率明显降低。在第6个月和第12个月，实验组的轴向长度增加明显少于对照组。短期佩戴角膜塑形镜可有效改善低度至中度近视青少年的裸眼视力，而不会对中央角膜厚度和角膜内皮细胞产生重大影响。这是矫正近视的相对安全的方法。第6个月和第12个月，而在这些时间点，实验组的屈光度显着低于对照组。在上述三个时间点，与对照组相比，实验组的角膜曲率明显降低。在第6个月和第12个月，实验组的轴向长度增加明显少于对照组。短期佩戴角膜塑形镜可有效改善低度至中度近视青少年的裸眼视力，而不会对中央角膜厚度和角膜内皮细胞产生重大影响。这是矫正近视的相对安全的方法。第6个月和第12个月，而在这些时间点，实验组的屈光度显着低于对照组。在上述三个时间点，与对照组相比，实验组的角膜曲率明显降低。在第6个月和第12个月，实验组的轴向长度增加明显少于对照组。短期佩戴角膜塑形镜可有效改善低度至中度近视青少年的裸眼视力，而对中央角膜厚度和角膜内皮细胞无明显影响。这是矫正近视的相对安全的方法。在上述三个时间点，与对照组相比，实验组的角膜曲率明显降低。在第6个月和第12个月，实验组的轴向长度增加明显少于对照组。短期佩戴角膜塑形镜可有效改善低度至中度近视青少年的裸眼视力，而不会对中央角膜厚度和角膜内皮细胞产生重大影响。这是矫正近视的相对安全的方法。在上述三个时间点，与对照组相比，实验组的角膜曲率明显降低。在第6个月和第12个月，实验组的轴向长度增加明显少于对照组。短期佩戴角膜塑形镜可有效改善低度至中度近视青少年的裸眼视力，而不会对中央角膜厚度和角膜内皮细胞产生重大影响。这是矫正近视的相对安全的方法。短期佩戴角膜塑形镜可有效改善低度至中度近视青少年的裸眼视力，而不会对中央角膜厚度和角膜内皮细胞产生重大影响。这是矫正近视的相对安全的方法。短期佩戴角膜塑形镜可有效改善低度至中度近视青少年的裸眼视力，而不会对中央角膜厚度和角膜内皮细胞产生重大影响。这是矫正近视的相对安全的方法。