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Subendometrial resistence and pulsatility index assessment of endometrial receptivity in assisted reproductive technology cycles.
Reproductive Biology and Endocrinology ( IF 4.2 ) Pub Date : 2019-08-02 , DOI: 10.1186/s12958-019-0507-6
R Silva Martins 1, 2 , A Helio Oliani 1 , D Vaz Oliani 1 , J Martinez de Oliveira 1, 2
Affiliation  

OBJECTIVE To evaluate Subendometrial and Uterine artery resistance and pulsatility index continuous analysis as a predictor of Endometrial receptivity in Assisted Reproductive Technology (ART) Cycles. DESIGN Serial 2D transvaginal coloured power doppler ultrasound performed in women on ART cycle to evaluate a pattern that better predicts implantation rates. One hundred sixty-nine subjects on a prospective case control study were assessed. Uterine artery and Subendometrial resistance and pulsatility index was performed to all subjects at baseline (prior to ovarian controlled stimulation), at day 6, 8 and 10 of controlled ovarian stimulation, at trigger day and at embryo transfer day. Also the ratio of fluxometric parameters between Subendometrial blood flow and uterine artery was measured. RESULTS No statistical difference was noted between two groups in terms of demographics and ART procedures and scores. Uterine artery resistance and pulsatility index showed statistical difference between the two groups (implantation versus non-implantation group). Also statistical significance was obtained between two groups in terms of Subendometrial vascularization. Ratio between Subendometrial and Uterine artery showed lower values of fluxometric parameters in all range for the Subendometrial territory. CONCLUSIONS Serial Subendometrial and Uterine artery fluxometry may be a useful tool for clinicians in predicting endometrial receptivity enhancing elective embryo transfers in the same ART cycle.

中文翻译:

辅助生殖技术周期中子宫内膜下容受性的子宫内膜下阻滞性和搏动性指数评估。

目的评估子宫内膜和子宫动脉阻力和搏动指数连续分析作为辅助生殖技术(ART)周期中子宫内膜容受性的预测指标。设计对女性在ART周期进行的连续2D经阴道彩色能量多普勒超声检查,以评估能更好地预测着床率的模式。对一项前瞻性病例对照研究的169名受试者进行了评估。在基线(卵巢控制刺激之前),卵巢控制刺激的第6、8和10天,触发日和胚胎移植日对所有受试者进行子宫动脉和子宫内膜下抵抗力和搏动指数。还测量子宫内膜下血流和子宫动脉之间的通量参数的比率。结果两组在人口统计学,抗逆转录病毒疗法和得分方面均无统计学差异。两组的子宫动脉阻力和搏动指数显示统计学差异(植入与非植入组)。两组之间的子宫内膜下血管形成也具有统计学意义。子宫内膜下动脉和子宫动脉之间的比率在子宫内膜下区域的所有范围内均显示出较低的通量参数。结论连续子宫内膜下和子宫动脉通量测定法可能是临床医生预测子宫内膜容受性的有用工具,可在同一ART周期内增强选择性胚胎的转移。两组的子宫动脉阻力和搏动指数显示统计学差异(植入与非植入组)。两组之间的子宫内膜下血管形成也具有统计学意义。子宫内膜下子宫和子宫动脉之间的比率在子宫内膜下区域的所有范围内均显示出较低的通量参数。结论连续子宫内膜下和子宫动脉通量测定法可能是临床医生预测子宫内膜容受性的有用工具,可在同一ART周期内增强选择性胚胎的转移。两组的子宫动脉阻力和搏动指数显示统计学差异(植入与非植入组)。两组之间的子宫内膜下血管形成也具有统计学意义。子宫内膜下子宫和子宫动脉之间的比率在子宫内膜下区域的所有范围内均显示出较低的通量参数。结论连续子宫内膜下和子宫动脉通量测定法可能是临床医生预测子宫内膜容受性的有效工具,可在同一ART周期内增强选择性胚胎的转移。子宫内膜下子宫和子宫动脉之间的比率在子宫内膜下区域的所有范围内均显示出较低的通量参数。结论连续子宫内膜下和子宫动脉通量测定法可能是临床医生预测子宫内膜容受性的有用工具,可在同一ART周期内增强选择性胚胎的转移。子宫内膜下子宫和子宫动脉之间的比率在子宫内膜下区域的所有范围内均显示出较低的通量参数。结论连续子宫内膜下和子宫动脉通量测定法可能是临床医生预测子宫内膜容受性的有用工具,可在同一ART周期内增强选择性胚胎的转移。
更新日期:2019-08-02
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