BACKGROUND Understanding the functional status of people with Alzheimer Disease (AD), both in a single (ST) and cognitive dual task (DT) activities is essential for identifying signs of early-stage neurodegeneration. This study aims to compare the performance quality of several tasks using sensors embedded in an Android device, among people at different stages of Alzheimer and people without dementia. The secondary aim is to analyze the effect of cognitive task performance on mobility tasks. METHODS This is a cross-sectional study including 22 participants in the control group (CG), 18 in the group with mild AD and 22 in the group with moderate AD. They performed two mobility tests, under ST and DT conditions, which were registered using an Android device. Postural control was measured by medial-lateral and anterior-posterior displacements of the COM (MLDisp and APDisp, respectively) and gait, with the vertical and medial-lateral range of the COM (Vrange and MLrange). Further, the sit-to-stand (PStand) and turning and sit power (PTurnSit), the total time required to complete the test and the reaction time were measured. RESULTS There were no differences between the two AD stages either for ST or DT in any of the variables (p > 0.05). Nevertheless, people at both stages showed significantly lower values of PStand and PTurnSit and larger Total time and Reaction time compared to CG (p < 0.05). Further, Vrange is also lower in CDR1G than in CG (p < 0.05). The DT had a significant deleterious effect on MLDisp in all groups (p < 0.05) and on APDisp only in moderate AD for DT. CONCLUSIONS Our findings indicate that AD patients present impairments in some key functional abilities, such as gait, turning and sitting, sit to stand, and reaction time, both in mild and moderate AD. Nevertheless, an exclusively cognitive task only influences the postural control in people with AD.

中文翻译：

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使用智能手机传感器对阿尔茨海默氏病患者的活动能力进行评估。

背景技术了解单次（ST）和认知双重任务（DT）活动中的阿尔茨海默病（AD）患者的功能状态对于识别早期神经退行性变的征兆至关重要。这项研究旨在比较处于Alzheimer不同阶段的人和没有痴呆症的人之间使用Android设备中嵌入的传感器进行的多项任务的性能质量。第二个目的是分析认知任务绩效对行动任务的影响。方法这是一项横断面研究，在对照组（CG）中包括22名参与者，轻度AD组中有18名参与者，中度AD组中有22名参与者。他们在ST和DT条件下执行了两项移动性测试，并使用Android设备进行了注册。姿势控制是通过COM的内侧-外侧和前后位置（分别为MLDisp和APDisp）和步态进行测量的，步态为COM的垂直和内侧-外侧范围（Vrange和MLrange）。此外，还测量了坐着站立时间（PStand）和旋转坐姿功率（PTurnSit），完成测试所需的总时间以及反应时间。结果ST或DT的两个AD阶段在任何变量上均无差异（p> 0.05）。但是，与CG相比，这两个阶段的人都显示出PStand和PTurnSit的值明显较低，而总时间和反应时间则较大（p <0.05）。此外，CDR1G中的Vrange也低于CG中的Vrange（p <0.05）。在所有组中，DT对MLDisp均具有显着的有害作用（p <0.05），而仅在中度AD中对DT具有APDisp的有害作用。结论我们的研究结果表明，在轻度和中度AD中，AD患者在某些关键功能能力（如步态，转身和坐姿，坐姿和反应时间）方面存在障碍。但是，仅认知任务只会影响AD患者的姿势控制。