BACKGROUND 3D non-contrast high-resolution black-blood cardiovascular magnetic resonance (CMR) (DANTE-SPACE) has been used for surveillance of abdominal aortic aneurysm (AAA) and validated against computed tomography (CT) angiography. However, it requires a long scan time of more than 7 min. We sought to develop an accelerated sequence applying compressed sensing (CS-DANTE-SPACE) and validate it in AAA patients undergoing surveillance. METHODS Thirty-eight AAA patients (all males, 73 ± 6 years) under clinical surveillance were recruited for this study. All patients were scanned with DANTE-SPACE (scan time 7:10 min) and CS-DANTE-SPACE (scan time 4:12 min, a reduction of 41.4%). Nine 9 patients were scanned more than 2 times. In total, 50 pairs of images were available for comparison. Two radiologists independently evaluated the image quality on a 1-4 scale, and measured the maximal diameter of AAA, the intra-luminal thrombus (ILT) and lumen area, ILT-to-muscle signal intensity ratio, and the ILT-to-lumen contrast ratio. The sharpness of the aneurysm inner/outer boundaries was quantified. RESULTS CS-DANTE-SPACE achieved comparable image quality compared with DANTE-SPACE (3.15 ± 0.67 vs. 3.03 ± 0.64, p = 0.06). There was excellent agreement between results from the two sequences for diameter/area and ILT ratio measurements (ICCs> 0.85), and for quantifying growth rate (3.3 ± 3.1 vs. 3.3 ± 3.4 mm/year, ICC = 0.95.) CS-DANTE-SPACE showed a higher ILT-to-lumen contrast ratio (p = 0.01) and higher sharpness than DANTE-SPACE (p = 0.002). Both sequences had excellent inter-reader reproducibility for quantitative measurements (ICC > 0.88). CONCLUSION CS-DANTE-SPACE can reduce scan time while maintaining image quality for AAA imaging. It is a promising tool for the surveillance of patients with AAA disease in the clinical setting.

中文翻译：

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使用压缩传感加速 3D 非对比黑血心血管磁共振 (CS-DANTE-SPACE) 监测腹主动脉瘤。


背景技术 3D 非对比高分辨率黑血心血管磁共振 (CMR) (DANTE-SPACE) 已用于监测腹主动脉瘤 (AAA)，并针对计算机断层扫描 (CT) 血管造影进行验证。然而，它需要7分钟以上的较长扫描时间。我们试图开发一种应用压缩感知 (CS-DANTE-SPACE) 的加速序列，并在接受监测的 AAA 患者中进行验证。方法 本研究招募了 38 名接受临床监测的 AAA 患者（均为男性，73 ± 6 岁）。所有患者均使用DANTE-SPACE（扫描时间7:10分钟）和CS-DANTE-SPACE（扫描时间4:12分钟，减少41.4%）进行扫描。 9名9名患者扫描次数超过2次。总共有 50 对图像可供比较。两名放射科医生独立评估图像质量，按 1-4 级评分，测量 AAA 最大直径、管腔内血栓 (ILT) 和管腔面积、ILT 与肌肉信号强度比以及 ILT 与管腔面积对比度。动脉瘤内/外边界的清晰度被量化。结果 与 DANTE-SPACE 相比，CS-DANTE-SPACE 实现了可比的图像质量（3.15 ± 0.67 与 3.03 ± 0.64，p = 0.06）。两个序列的直径/面积和 ILT 比率测量结果 (ICC> 0.85) 以及量化生长率 (3.3 ± 3.1 与 3.3 ± 3.4 毫米/年，ICC = 0.95) 的结果非常一致。CS-DANTE与 DANTE-SPACE (p = 0.002) 相比，-SPACE 显示出更高的 ILT 与流明对比度 (p = 0.01) 和更高的清晰度。两个序列在​​定量测量方面都具有出色的读数器间重现性（ICC > 0.88）。结论 CS-DANTE-SPACE 可以减少扫描时间，同时保持 AAA 成像的图像质量。 它是在临床环境中监测 AAA 疾病患者的一个有前途的工具。