BACKGROUND People who inject drugs (PWID) in Kazakhstan face many barriers to HIV testing as well as to accessing HIV care, to retention in HIV care, and to initiating and adhering to anti-retroviral treatment (ART). Needle and syringe programs (NSPs) are an opportune setting for integrated interventions to link PWID to HIV care. METHODS This Hybrid Type II study employs a stepped-wedge design to evaluate both effectiveness and implementation outcomes of Bridge, an intervention to identify, test, and link HIV-positive PWID to HIV care. The study is conducted at 24 NSPs in three different regions of Kazakhstan, to assess outcomes on the individual, organizational, and policy levels. DISCUSSION This trial responds to an identified need for new models of HIV service delivery for PWID through harm reduction settings. TRIAL REGISTRATION NCT02796027 on June 10, 2016.

中文翻译：

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改善哈萨克斯坦注射吸毒者的艾滋病毒服务提供：Bridge 阶梯楔形试验研究方案。

背景技术哈萨克斯坦的注射吸毒者（PWID）在艾滋病毒检测、获得艾滋病毒护理、继续接受艾滋病毒护理以及开始和坚持抗逆转录病毒治疗（ART）方面面临许多障碍。针头和注射器计划 (NSP) 是将吸毒者与艾滋病毒护理联系起来的综合干预措施的有利环境。方法 这项混合 II 型研究采用阶梯式楔形设计来评估 Bridge 的有效性和实施结果，Bridge 是一种识别、测试 HIV 阳性吸毒者并将其与 HIV 护理联系起来的干预措施。该研究在哈萨克斯坦三个不同地区的 24 个国家服务提供商进行，旨在评估个人、组织和政策层面的成果。讨论 本试验满足了通过减少危害环境为吸毒者提供艾滋病毒服务新模式的需求。2016 年 6 月 10 日试用注册 NCT02796027。