BACKGROUND Health-related organisations disseminate an abundance of clinical and implementation evidence that has potential to improve health outcomes in low- and middle-income countries (LMICs), but little is known about what influences a user decision to select particular evidence for action. Knowledge brokers (KBs) play a part as intermediaries supporting evidence-informed health policy and practice by selecting and synthesising evidence for research users, and therefore understanding the basis for KB decisions, can help inform knowledge translation strategies. The Theoretical Domains Framework (TDF), a synthesis of psychological theories, was selected as a promising analysis approach because of its widespread use in identifying influences on decisions to act on evidence-based healthcare guidelines. This study explored its application in the context of KB decisions regarding evidence for use in LMICs. METHODS The study analysed data collected from participants of a 2015 global maternal and newborn health conference in Mexico. A total of 324 conference participants from 56 countries completed an online survey and 20 from 15 countries were interviewed about evidence use and sharing after the conference. TDF domains and constructs were retrospectively applied and adapted during coding of qualitative data to enhance understanding of the KB decision process in selecting evidence for action. RESULTS Application of the TDF involved challenges related to overlapping constructs, retrospective use, and complexities of global health settings and relevant knowledge. Codes needed to be added or adapted to account for how KBs' internal reflections on external factors influenced their actions in selecting evidence to share and use, and the decisions they made during the process. Four themes of the rationale for changing the TDF were identified during analysis, namely Influences from Beyond the Organisation, Knowledge Selection as a Process, Access and Packaging of Knowledge, and Fit for Use. CONCLUSIONS Theories of individual behaviour, such as those in the TDF, can enhance understanding of the decisions made by actors such as KBs along dissemination and knowledge translation pathways. Understanding how KBs reflect on evidence and interact with their environment has the potential for improving global dissemination efforts and LMIC-to-LMIC exchange of implementation evidence.

中文翻译：

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应用理论领域框架来理解知识经纪人的决策，从而为中低收入国家的知识翻译选择证据。

背景技术与健康有关的组织在中低收入国家（LMIC）中散布了大量有可能改善健康结果的临床和实施证据，但对于影响用户选择特定证据以采取行动的决定的影响知之甚少。知识经纪人（KBs）作为中介机构，通过为研究用户选择和综合证据来支持循证的卫生政策和实践，因此发挥了作用，因此了解知识库决策的基础可以帮助为知识翻译策略提供信息。心理领域的综合理论领域框架（TDF）被选为有前途的分析方法，因为它广泛用于识别对基于循证医疗保健准则的决策的影响。这项研究在有关LMIC中使用证据的KB决策中探索了其应用。方法该研究分析了从2015年墨西哥全球孕产妇和新生儿健康会议参与者收集的数据。来自56个国家/地区的324名与会人员完成了一项在线调查，并在会后对15个国家/地区的20名与会人员进行了关于证据使用和共享的采访。在对定性数据进行编码时，对TDF域和结构进行了追溯性应用和调整，以增强对KB决策过程的理解，以选择行动证据。结果TDF的应用涉及与重叠的结构，回顾性使用以及全球卫生环境和相关知识的复杂性有关的挑战。需要添加或修改代码以说明KB的方式 对外部因素的内部思考影响了他们在选择要共享和使用的证据时所采取的行动，以及他们在此过程中做出的决定。在分析过程中，确定了更改TDF的基本原理的四个主题，即来自组织之外的影响，作为过程的知识选择，知识的获取和包装以及适合使用。结论个人行为的理论，例如TDF中的理论，可以增进对诸如知识库（KB）等行为者在传播和知识转化途径上所做决定的理解。了解知识库如何反映证据并与其环境互动，有可能改善全球传播工作以及实施证据的LMIC到LMIC的交换。以及他们在此过程中所做的决定。在分析过程中，确定了更改TDF的基本原理的四个主题，即来自组织之外的影响，作为过程的知识选择，知识的获取和包装以及适合使用。结论个人行为的理论，例如TDF中的理论，可以增进对诸如知识库（KB）等行为者在传播和知识转化途径上所做决定的理解。理解知识库如何反映证据并与其环境互动，有可能改善全球传播工作以及实施证据的LMIC到LMIC的交换。以及他们在此过程中所做的决定。在分析过程中，确定了更改TDF的基本原理的四个主题，即来自组织之外的影响，作为过程的知识选择，知识的获取和包装以及适合使用。结论个人行为的理论，例如TDF中的理论，可以增进对诸如知识库（KB）等行为者在传播和知识转化途径上所做决定的理解。了解知识库如何反映证据并与其环境互动，有可能改善全球传播工作以及实施证据的LMIC到LMIC的交换。获取和打包知识，并适合使用。结论个人行为的理论，例如TDF中的理论，可以增进对诸如知识库（KB）等行为者在传播和知识转化途径上所做决定的理解。了解知识库如何反映证据并与其环境互动，有可能改善全球传播工作以及实施证据的LMIC到LMIC的交换。获取和打包知识，并适合使用。结论个人行为的理论，例如TDF中的理论，可以增进对诸如知识库（KB）等行为者在传播和知识转化途径上所做决定的理解。了解知识库如何反映证据并与其环境互动，有可能改善全球传播工作以及实施证据的LMIC到LMIC的交换。