The sciences, and especially the research subspecialties of occupational and environmental health, are being misused. The misuse serves to interfere with the advancement of policies that depend on rational evidence needed for policies to protect public health. We selectively surveyed the independent scientific literature. In addition, the efforts of respected international professional organizations of scientists whose focus is on maintaining and improving public health have been considered. This commentary is unique in assembling not only the factual basis for sounding alarms about significant bias in occupational and environmental health research, but also about the manipulative mechanisms used, and, in turn, the methods needed to keep science honest. Scientific integrity is based on the principle that research is conducted as objectively as possible; it cannot be compromised by special interests whose primary goals are neither to seek truth nor to protect human health. Evidence demonstrates a significant risk of bias in research reports sponsored by financial interests. Practices of corporate malfeasance include the orchestrated contamination of editorial boards of peer-reviewed scientific journals with industry apologists; interference with activities of national regulatory bodies and international review panels engaged in safeguarding occupational and public health; constructing roadblocks by capitalizing on uncertainty to undermine scientific consensus for much-needed government regulation of carcinogenic, endocrine-disrupting and/or immunotoxic agents; promoting “causation” criteria that lack foundation and effectively block workers’ access to legal remedies for harms from occupational exposures resulting in morbidity and premature mortality; and, violating standards of professional conduct by seducing reputable scientists with financial incentives that make them beholden to corporate agendas. Well-orchestrated assaults on science continue unabated and must now be met head-on. Success could be achieved by promoting and protecting the integrity of research. Furthermore, avoiding influence by conflicted corporate affiliates in occupational and public health regulations is needed. Identifying, managing and, ideally, eliminating corporate influence on science and science policy are needed to protect research integrity. Protecting the public’s health, preventing disease, and promoting well-being must be the unambiguous goals of research in occupational and environmental health.

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在利益冲突的情况下，如何保持职业和环境卫生研究的完整性？

科学，尤其是职业和环境卫生的研究子专业，被滥用了。滥用会干扰政策的发展，而政策的发展依赖于保护公众健康的政策所需的合理证据。我们有选择地调查了独立的科学文献。此外，还考虑了受人尊敬的国际专业科学家组织的努力，这些组织的重点是维持和改善公共卫生。这篇评论的独特之处在于，它不仅汇集了对职业和环境卫生研究中存在重大偏见发出警报的事实基础，而且还汇集了所使用的操纵机制，以及反过来保持科学诚实所需要的方法。科学诚信基于尽可能客观地进行研究的原则；它的主要目的既不是寻求真相也不是保护人类健康的特殊利益不能损害它。证据表明，由财务利益发起的研究报告存在很大的偏见风险。公司渎职行为包括精心策划的同行评议科学期刊编辑委员会受到行业辩护人的污染；干扰从事维护职业和公共卫生的国家监管机构和国际审查小组的活动；通过利用不确定性来构筑障碍，以破坏政府对致癌，内分泌干扰和/或免疫毒性剂急需的监管的科学共识；推广缺乏基础的“因果关系”标准，并有效地阻止工人因职业暴露而导致疾病和过早死亡的危害而寻求法律救济；并通过以财务激励诱使知名科学家成为公司议程的行为，从而违反了专业行为标准。精心策划的对科学的攻击仍未减弱，现在必须直面。可以通过促进和保护研究的完整性来取得成功。此外，需要避免受到冲突的公司分支机构在职业和公共卫生法规中的影响。为了保护研究的完整性，需要识别，管理以及理想情况下消除公司对科学和科学政策的影响。保护公众健康，预防疾病，