We tested whether childhood adversity is associated with poor cardiometabolic health in adulthood among a sample of overweight or obese Dutch women of reproductive age. Health behaviors, psychological distress, mood symptoms, or personality traits were included as potential mediators. Data came from a follow-up visit (N = 115), carried out in 2016/2017, of a randomized controlled lifestyle intervention trial in 577 obese infertile women. The associations between total adversity exposure score and cardiometabolic health were tested with regression models. Sleep, smoking and eating behavior, symptoms of depression, anxiety and stress, and personality traits were potential mediators. Childhood adversity scores were not associated with cardiometabolic outcomes but were associated with poorer sleep quality score (M = 7.2 (SD = 3.5) for those with ≥2 types of events versus 4.8 (2.9) for those with no events; p = 0.022), higher external eating score (26.4 (8.7) versus 21.8 (10.3); p = 0.038), higher perceived stress score (17.1 (6.8) versus 12.3 (4.5); p = 0.016), post-traumatic stress score (1.9 (1.5) versus 0.6 (1.1); p < 0.001), and lower agreeableness score (28.2 (4.2) versus 30.3 (3.1); p = 0.035). Childhood adversity was associated with poorer health behaviors including sleep and eating behavior, and more stress-related symptoms, but not with women’s cardiometabolic health.

中文翻译：

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童年时期的逆境与女性的心脏代谢健康：与健康行为，心理困扰，情绪症状和性格的关联

我们在一个超重或肥胖的育龄荷兰妇女样本中测试了童年逆境与成年后不良的心脏代谢健康是否相关。健康行为，心理困扰，情绪症状或人格特质均被列为潜在的媒介。数据来自2016/2017年对577名肥胖不育女性进行的一项随机对照生活方式干预试验的随访（N = 115）。使用回归模型测试了总逆境暴露得分与心脏代谢健康之间的关联。睡眠，吸烟和进食行为，抑郁症，焦虑和压力症状以及人格特质是潜在的媒介。儿童逆境评分与心脏代谢结果无关，但与较差的睡眠质量评分相关（M = 7.2（SD = 3）。5）对于事件类型≥2的那些，而没有事件类型的那些为4.8（2.9）；p = 0.022），较高的外部进食分数（26.4（8.7）与21.8（10.3）; p = 0.038），较高的感知压力分数（17.1（6.8）与12.3（4.5）; p = 0.016），创伤后压力分数（1.9（1.5）对0.6（1.1）； p <0.001）和较低的可喜度评分（28.2（4.2）对30.3（3.1）； p = 0.035）。童年时期的逆境与较差的健康行为（包括睡眠和进食行为）以及更多与压力相关的症状有关，而与妇女的心脏代谢健康无关。以及较低的一致性得分（28.2（4.2）和30.3（3.1）； p = 0.035）。童年时期的逆境与较差的健康行为（包括睡眠和进食行为）以及更多与压力相关的症状有关，而与妇女的心脏代谢健康无关。以及较低的一致性得分（28.2（4.2）和30.3（3.1）； p = 0.035）。童年时期的逆境与较差的健康行为（包括睡眠和进食行为）以及更多与压力相关的症状有关，而与妇女的心脏代谢健康无关。