当前位置: X-MOL 学术BMC Urol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Penile metastasis from recurrent sarcoma in a teenager: a case report.
BMC Urology ( IF 1.7 ) Pub Date : 2019-09-02 , DOI: 10.1186/s12894-019-0511-3
Chi-Fang Chen,Tzu-Ying Tang,Marcelo Chen,Li-Chen Chen

BACKGROUND Metastatic tumors of the penis are uncommon, and fewer than 500 cases have been reported since 1870. Most penile secondary tumors originate in organs of the genitourinary tract, followed by the gastrointestinal tract. Primary tumors of sarcoma origin are extremely rare. Herein, we present a teenager who had recurrent sarcoma of the right femur with penile metastasis. CASE PRESENTATION The 20-year-old male patient was diagnosed with sarcoma of the right femur when he was 16 days old. He was stable following combination chemotherapy with the VAC regimen (vincristine, adriamycin, and cyclophosphamide) and debulking surgery. In January 2018, five months ago, he presented with right leg pain and swelling, and a recurrent tumor was found. Following excision of the tumor showed recurrent sarcoma. However, 2 months after the operation, right thigh swelling with tenderness occurred. A firm nodule on the glans of the penis was also noted. Penile metastasis was suspected and a biopsy was performed. The final pathology report disclosed pleomorphic sarcoma with penile metastasis. Symptoms including priapism and inguinal lymph node enlargement progressed rapidly within 2 weeks. He also complained of voiding difficulty with urine retention. The patient died 35 days after admission due to pneumonia with septic shock. CONCLUSION Penile metasitasis largely occurs from organs in the pelvis. To the best of our knowledge, this is the first case of a teenager with a secondary penile tumor, metastasizing from sarcoma of the bone. It presented as a palpable mass, and then progressed into priapism. The patient had a dismal prognosis and the symptoms progressed faster than his physicians anticipated.

中文翻译:

青少年复发性肉瘤阴茎转移:病例报告。

背景技术阴茎转移性肿瘤并不常见,自1870年以来报道的病例不到500例。大多数阴茎继发性肿瘤起源于泌尿生殖道器官,其次是胃肠道。肉瘤起源的原发性肿瘤极为罕见。在此,我们介绍了一名患有右股骨肉瘤复发并伴有阴茎转移的青少年。病例介绍 这名20岁的男性患者在出生16天时被诊断出患有右侧股骨肉瘤。在接受 VAC 方案(长春新碱、阿霉素和环磷酰胺)联合化疗和减瘤手术后,他的病情稳定。2018年1月,也就是5个月前,他出现右腿疼痛、肿胀,并发现肿瘤复发。肿瘤切除后显示肉瘤复发。然而,术后2个月,右大腿出现肿胀、压痛。还注意到阴茎龟头上有一个坚硬的结节。怀疑阴茎转移并进行了活检。最终病理报告显示多形性肉瘤伴阴茎转移。阴茎异常勃起和腹股沟淋巴结肿大等症状在两周内迅速进展。他还抱怨尿潴留导致排尿困难。患者入院 35 天后因肺炎合并感染性休克死亡。结论 阴茎转移主要发生在骨盆器官。据我们所知,这是青少年患有继发性阴茎肿瘤的第一例,该肿瘤由骨肉瘤转移。它表现为可触及的肿块,然后发展为阴茎异常勃起。该患者的预后很差,而且症状的进展速度比医生预期的要快。
更新日期:2019-09-02
down
wechat
bug