Concurrent presentation of retinal vasculitis with mixed sclerotic and lytic bone lesions is rare. We present the case of a 37-year old woman with a several year history of episodic sternoclavicular pain who presented for rheumatologic evaluation due to a recent diagnosis of retinal vasculitis. We review the differential diagnosis of retinal vasculitis, along with the differential diagnosis of mixed sclerotic and lytic bone lesions. Ultimately, bone marrow biopsy confirmed diagnosis of chronic recurrent multifocal osteomyelitis (CRMO). Concurrent presentation of CRMO with retinal vasculitis is extremely rare but important to recognize. The patient demonstrated clinical response to prednisone and tumor necrosis factor-alpha inhibition (TNF-i). This case reports and unusual presentation of CRMO spectrum disease involving the sternum and sternoclavicular joint with concurrent retinal vasculitis.

中文翻译：

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视网膜血管炎伴慢性复发性多灶性骨髓炎1例报告并文献复习

合并硬化性和溶骨性病变的视网膜血管炎很少见。我们介绍了一名 37 岁女性的病例，她有几年的阵发性胸锁痛病史，由于最近诊断出视网膜血管炎而进行风湿病学评估。我们回顾了视网膜血管炎的鉴别诊断，以及混合性硬化性和溶解性骨病变的鉴别诊断。最终，骨髓活检证实了慢性复发性多灶性骨髓炎（CRMO）的诊断。CRMO 与视网膜血管炎的并发表现极为罕见，但需要识别。患者表现出对泼尼松和肿瘤坏死因子-α抑制 (TNF-i) 的临床反应。