Nowadays there is a growing interest in exploring causes of fatigue symptoms and the possible linked aspects in patients with Chronic Kidney Disease (CKD) receiving hemodialysis (HD) treatment. Inflammatory processes were demonstrated to influence motivational systems functioning in chronic conditions. However, there is a lack of connection between quantitative motivational systems measure and patients self-report motivational and fatigue issue. Thus, the aim of this study was to identify an association between HD patients reward mechanisms, fatigue severity and psychosocial variables emerging from semi-structured interviews. Interviews were held for a sample of ninety-four patients (54 males, 40 females; Mage = 62.98 ± 17.94; dialytic mean age in months = 76.55 ± 84.89) receiving chronic HD treatment and consequently analyzed by means of quantitative and qualitative analysis. Behavioral motivation systems reflecting inhibition/approach tendency to rewards were measured by Behavioral Inhibition/Activation System (BIS/BAS) scale and the fatigue severity experienced by HD patients was measured with the Fatigue Severity Scale. Scale results were correlated to psychosocial variables and topics derived from the semi-structured interviews. Findings highlight the presence of two effects: one related to the Behavioral Activation System (BAS) as a protective factor against the HD treatment pervasive consequences; the other one deals with the self-reported levels of fatigue that seemed to significantly interfere with patients’ daily life, as a function of gender. Such results encourage the use of a mixed method approach to understand the complexity of the subjective experience of patients’ facing chronic disease and treatments.

中文翻译：

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血液透析治疗中疲劳，动机措施（BIS / BAS）与半结构式心理社会访谈之间的关联

如今，越来越有兴趣探索接受血液透析（HD）治疗的慢性肾脏病（CKD）患者的疲劳症状的原因以及可能的相关方面。实验证明，炎症过程会影响慢性条件下的动机系统。但是，定量激励系统度量与患者自我报告的激励和疲劳问题之间缺乏联系。因此，本研究的目的是确定HD患者报酬机制，疲劳严重程度与半结构化访谈中出现的社会心理变量之间的关联。对94名患者进行了访谈（男54例，女40例；法师= 62.98±17.94；数月透析平均年龄= 76.55±84。89）接受慢性HD治疗，因此通过定量和定性分析进行分析。通过行为抑制/激活系统（BIS / BAS）量表来衡量反映抑制/接近奖励趋势的行为动机系统，并通过疲劳严重度量表来衡量HD患者经历的疲劳严重程度。量表的结果与社会心理变量和从半结构化访谈中得出的主题相关。研究结果突出了两种作用的存在：一种与行为激活系统（BAS）有关，作为防止HD治疗普遍后果的保护因子；另一种与行为激活系统（BAS）有关。另一类涉及自我报告的疲劳水平，该水平似乎显着干扰患者的日常生活，这是性别的函数。