Vitamin D deficiency has been observed worldwide in pregnant women and their newborns. Maternal vitamin D deficiency can lead to deficiency in their newborn baby and has been linked with various complications during pregnancy and delivery. There is risk of premature delivery and it is associated with high neonatal mortality. Seventy-nine pregnant women who were admitted to the Siddhi Memorial Hospital for delivery and their newborn babies were enrolled in the study. Maternal blood samples were taken before delivery while umbilical cord blood samples of their babies were taken after delivery. Serum vitamin D level and calcium level were assessed by fluorescence immunoassay using Ichromax vitamin D kit and endpoint method, respectively in the Siddhi Memorial Hospital laboratory. Mean +/− SD serum vitamin D and calcium levels in pregnant mother before delivery were 14.6 +/− 8.5 ng/ml and 8.0 +/− 0.5 mg/dl, respectively, and in the cord blood were 25.7 +/− 11.2 ng/ml and 8.6 +/− 0.9 mg/dl, respectively. Eighty-one percent of the mothers and 35.8% of their babies were found to have vitamin D deficiency. Although 97.5% of the pregnant women were taking calcium supplementation, serum calcium was found lower than the normal reference value in 67% of the pregnant women and 64.2% of their babies. There were a linear relationship between the maternal and baby’s serum vitamin D (P < 0.001) and calcium (P < 0.001) levels. There is high prevalence of vitamin D and calcium deficiency in pregnant mothers and newborn babies in Bhaktapur, Nepal. Pregnant women need to be supplemented with adequate amounts of these nutrients.

中文翻译：

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尼泊尔巴克塔普尔孕妇及其婴儿维生素 D 缺乏症的患病率

全世界都观察到孕妇及其新生儿缺乏维生素 D。母亲维生素 D 缺乏会导致新生儿缺乏维生素 D，并且与怀孕和分娩期间的各种并发症有关。存在早产的风险，并且与高新生儿死亡率相关。79 名被送往 Siddhi 纪念医院分娩的孕妇及其新生婴儿参加了这项研究。产妇的血液样本是在分娩前采集的，而他们的婴儿的脐带血样本是在分娩后采集的。血清维生素 D 水平和钙水平分别在 Siddhi 纪念医院实验室使用 Ichromax 维生素 D 试剂盒和终点法通过荧光免疫测定法进行评估。孕妇分娩前平均 +/- SD 血清维生素 D 和钙水平分别为 14.6 +/- 8.5 ng/ml 和 8.0 +/- 0.5 mg/dl，脐带血中为 25.7 +/- 11.2 ng/ ml 和 8.6 +/- 0.9 mg/dl，分别。81% 的母亲和 35.8% 的婴儿被发现缺乏维生素 D。虽然97.5%的孕妇在补钙，但67%的孕妇和64.2%的婴儿血清钙低于正常参考值。母婴血清维生素D（P < 0.001）和钙（P < 0.001）水平呈线性关系。尼泊尔巴克塔普尔的孕妇和新生儿普遍缺乏维生素 D 和钙。孕妇需要补充足量的这些营养素。