BACKGROUND To evaluate the diagnostic accuracy of the median-to-ulnar nerve ratio (MUR) and the median-to-ulnar nerve difference (MUD) in patients with carpal tunnel syndrome (CTS). METHODS In this study, 32 patients with CTS and 32 healthy volunteers were evaluated. All participants received a series of tests and ultrasound examination for the evaluation of the following criteria: cross-sectional area of the median nerve at the pisiform level (CSA-P), swelling ratio (SR), MUR, MUD, and flattening ratio (FR). RESULTS CSA-P, SR, MUR, and MUD were all significantly larger in the patients with CTS than in the healthy volunteers. The areas under the receiver operator characteristic curves of MUD, MUR, CSA-P, and SR were 0.78, 0.75, 0.70, and 0.61 respectively. MUD had higher sensitivity (84%) than MUR, CSA-P, and SR (sensitivity: 63, 63, and 53%, respectively). CONCLUSIONS By using the ulnar nerve area at the pisiform level as an internal control parameter, the MUD and MUR methods showed higher diagnostic accuracy than SR in patients with CTS. Further application of these methods in research and clinical settings is recommended. TRIAL REGISTRATION Clinicaltrial.gov NCT03033173. Registered 18 January 2017. Retrospectively registered.

中文翻译：

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诊断腕管综合征的正中神经与尺神经截面积之比及差异：病例对照研究。

背景技术为了评估腕管综合症（CTS）患者中尺神经比（MUR）和中尺神经差（MUD）的诊断准确性。方法在本研究中，对32名CTS患者和32名健康志愿者进行了评估。所有参与者均接受了一系列测试和超声检查，以评估以下标准：梨状肌水平的正中神经截面积（CSA-P），肿胀率（SR），MUR，MUD和展平率（ FR）。结果CTS患者的CSA-P，SR，MUR和MUD均显着大于健康志愿者。MUD，MUR，CSA-P和SR的接收器操作员特征曲线下的面积分别为0.78、0.75、0.70和0.61。MUD的敏感性（84％）高于MUR，CSA-P和SR（敏感性分别为63％，63％和53％，分别）。结论通过使用尺状神经的尺神经区域作为内部控制参数，MUD和MUR方法对CTS患者的诊断准确性高于SR。建议在研究和临床环境中进一步应用这些方法。试用注册Clinicaltrial.gov NCT03033173。2017年1月18日注册。追溯注册。