BACKGROUND The invasive method for intracranial pressure measurement is 'gold standard' but not always feasible because the intraventricular catheter/ intraparenchymal micro transducer used in the measurement of intracranial pressure measurement may cause complications. Imaging modalities with clinical examination protocol have a lack of specificity and accuracy. The objective of the study was to compare the accuracy of diagnostic parameters of ultrasound measurements in patients with brain injury underwent invasive intracranial pressure measurement method. METHODS Data of invasive intracranial pressure measurement method and ultrasound measurements of 185 patients with brain injury who required admission diagnosis were included in the analysis. Pearson correlation was tested for diagnostic parameters. Logistical regression analysis was performed for diagnostic parameters of death patients to evaluate independent parameter of mortality. RESULTS Straight sinus flow velocities, middle cerebral artery flow velocities, and optic nerve sheath diameter were correlated with intracranial pressure (p < 0.0001 for all). Arterial blood pressure (p = 0.127) and middle cerebral artery pulsatility index (p = 0.06) were not correlated with intracranial pressure. A total of 47 patients died during the study period. Intracranial pressure (p = 0.015) and optic nerve sheath diameter (p = 0.035) were found to be independent predictor of mortality. CONCLUSIONS Ultrasound measurement especially optic nerve sheath diameter can be successfully used instead of invasive intracranial pressure measurement method in patients with brain injury. LEVEL OF EVIDENCE III.

中文翻译：

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颅脑损伤患者的超声测量与有创颅内压测量方法：一项回顾性研究。

背景技术颅内压测量的有创方法是“黄金标准”，但并不总是可行的，因为在颅内压测量中使用的脑室内导管/实质内微型换能器可能会引起并发症。具有临床检查方案的成像方式缺乏特异性和准确性。本研究的目的是比较接受颅内压测量的颅脑损伤患者超声测量诊断参数的准确性。方法分析185例需要入院诊断的颅脑损伤患者的侵入性颅内压测量方法和超声测量数据。对Pearson相关性进行了诊断参数测试。对死亡患者的诊断参数进行逻辑回归分析，以评估独立的死亡率参数。结果窦直流速，大脑中动脉流速和视神经鞘管直径均与颅内压相关（所有p <0.0001）。动脉血压（p = 0.127）和大脑中动脉搏动指数（p = 0.06）与颅内压无关。在研究期间共有47名患者死亡。发现颅内压（p = 0.015）和视神经鞘管直径（p = 0.035）是死亡率的独立预测因子。结论在脑损伤患者中，超声测量，尤其是视神经鞘管直径测量可成功替代有创颅内压测量方法。证据级别III。