BACKGROUND The value of magnetic resonance imaging (MRI), contrast-enhanced ultrasound (CEUS), and the combination of CEUS and MRI (CCWM) for the diagnosis of periampullary space-occupying lesions (PSOL) was investigated. METHODS A total of 102 patients diagnosed with PSOLs by surgery or biopsy were recruited retrospectively. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of MRI, CEUS, and CCWM were analyzed. RESULTS MRI, CEUS, and CCWM allowed for the accurate detection of 91.17, 92.15, and 99.01% of PSOLs, respectively. The specificity, PPV, and accuracy of CCWM were significantly different from MRI and CEUS (p < 0.05). However, there the sensitivity and NPV were not significantly different among the three diagnostic technologies. In addition, the specificity, PPV, and accuracy were not significantly different between MRI and CEUS (all p > 0.05). CONCLUSIONS CCWM is valuable for differentiating benign and malignant PSOL, which provides important guiding significances for the clinic.

中文翻译：

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CEUS和MRI的结合用于壶腹周围占位性病变的诊断：回顾性分析。

背景技术研究了磁共振成像（MRI），对比增强超声（CEUS）以及CEUS和MRI组合（CCWM）在壶腹周围占位性病变（PSOL）诊断中的价值。方法回顾性分析102例经手术或活检诊断为PSOL的患者。分析了MRI，CEUS和CCWM的敏感性，特异性，阳性预测值（PPV），阴性预测值（NPV）和准确性。结果MRI，CEUS和CCWM分别可准确检测91.17％，92.15％和99.01％的PSOL。CCWM的特异性，PPV和准确性与MRI和CEUS显着不同（p <0.05）。但是，三种诊断技术之间的灵敏度和NPV并无显着差异。此外，特异性，PPV，MRI和CEUS之间的准确性和准确性无显着差异（所有p> 0.05）。结论CCWM对于区分良恶性PSOL具有重要价值，为临床提供重要的指导意义。