A copper(I)-mediated tandem three-component reaction using alkynes, azides, allyl iodides, CuI and NaNH₂ is developed. The reactions proceed smoothly at room temperature to afford 5-allyl-1,2,3-triazoles, which can be further converted into 1,2,3-triazole-fused tricyclic scaffolds. This method features an efficient one-pot cascade route using commercial alkynes and affords the corresponding 5-allyl-1,2,3-triazoles with high yields and good selectivity under mild reaction conditions.

中文翻译：

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铜（I）介导的5-烯丙基1,2,3-三唑的串联三组分合成

开发了使用炔烃，叠氮化物，烯丙基碘，CuI和NaNH ₂的铜（I）介导的串联三组分反应。反应在室温下平稳进行，得到5-烯丙基-1,2,3-三唑，其可以进一步转化为1,2,3-三唑稠合的三环支架。该方法的特点是使用商业炔烃的高效一锅级联途径，并在温和的反应条件下以高收率和良好的选择性提供了相应的5-烯丙基-1,2,3-三唑。