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Macrophage‐derived progranulin promotes allergen‐induced airway inflammation
Allergy ( IF 12.6 ) Pub Date : 2020-01-31 , DOI: 10.1111/all.14129
Jun-Pyo Choi 1 , So Young Park 2 , Keun-Ai Moon 1 , Eun Hee Ha 1 , Yeon Duk Woo 3 , Doo Hyun Chung 3 , Hyouk-Soo Kwon 1 , Tae-Bum Kim 1 , Hae-Sim Park 4 , Hee-Bom Moon 1 , Woo-Jung Song 1 , You Sook Cho 1
Affiliation  

Progranulin (PGRN), mainly produced by immune and epithelial cells, has been known to be involved in the development of various inflammatory diseases. However, the function of PGRN in allergic airway inflammation has not been clearly elucidated, and we investigated the role of PGRN in allergic airway inflammation.

中文翻译:

巨噬细胞衍生的颗粒蛋白前体促进过敏原诱导的气道炎症

颗粒蛋白前体 (PGRN) 主要由免疫细胞和上皮细胞产生,已知参与各种炎症性疾病的发展。然而,PGRN 在过敏性气道炎症中的作用尚未明确阐明,我们研究了 PGRN 在过敏性气道炎症中的作用。
更新日期:2020-01-31
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