This article is part of the Central Nervous System-Related Pathogens special issue. Central nervous system (CNS) infections caused by viruses, bacteria, fungi, and protozoa can be life-threatening if not rapidly diagnosed and treated. Moreover, many emerging and rare CNS infections lack effective therapies and/or diagnostics. The development of new molecular diagnostics, novel therapeutic strategies, and model systems of CNS and related infections remains a high research priority. The collection of manuscripts in this ACS Infectious Diseases Central Nervous System-Related Pathogens Special Issue illustrates the intersection of chemistry and CNS infectious disease research. These manuscripts span a range of topics, showcasing novel antivirals for neurotropic viruses, development of PET and radioisotopic probes to study drug uptake and imaging in the brain, small molecules and nanoparticles for the treatment of brain-eating amoebic infections, and the challenges of treating bacterial meningitis. In closing, I would like to express my gratitude to the authors and reviewers for their contributions to this special issue. ACS Infectious Diseases encourages the continued submission of high-quality research Articles, Reviews, and Viewpoints exploring CNS infections. Views expressed in this editorial are those of the author and not necessarily the views of the ACS. This article has not yet been cited by other publications.

中文翻译：

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中枢神经系统相关病原体。

本文是 中枢神经系统相关病原体特刊。如果不迅速诊断和治疗，由病毒，细菌，真菌和原生动物引起的中枢神经系统（CNS）感染可能危及生命。此外，许多新兴的和罕见的中枢神经系统感染缺乏有效的治疗方法和/或诊断方法。开发新的分子诊断方法，新的治疗策略以及中枢神经系统及其相关感染的模型系统仍然是研究的重中之重。本ACS传染病中的手稿的收集中枢神经系统相关病原体特刊阐述了化学与中枢神经系统传染病研究的交叉点。这些手稿涵盖了多个主题，展示了用于神经营养性病毒的新型抗病毒药，开发PET和放射性同位素探针以研究大脑中的药物吸收和成像，用于治疗食人性阿米巴感染的小分子和纳米颗粒以及治疗挑战细菌性脑膜炎。最后，我要感谢作者和审稿人对这一特刊的贡献。ACS传染病鼓励继续提交高质量的研究文章，评论和观点，探讨中枢神经系统感染。本社论中表达的观点只是作者的观点，不一定是ACS的观点。本文尚未被其他出版物引用。