Skin-mounted soft electronics that incorporate high-bandwidth triaxial accelerometers can capture broad classes of physiologically relevant information, including mechano-acoustic signatures of underlying body processes (such as those measured by a stethoscope) and precision kinematics of core-body motions. Here, we describe a wireless device designed to be conformally placed on the suprasternal notch for the continuous measurement of mechano-acoustic signals, from subtle vibrations of the skin at accelerations of around 10-3 m s-2 to large motions of the entire body at about 10 m s-2, and at frequencies up to around 800 Hz. Because the measurements are a complex superposition of signals that arise from locomotion, body orientation, swallowing, respiration, cardiac activity, vocal-fold vibrations and other sources, we exploited frequency-domain analysis and machine learning to obtain-from human subjects during natural daily activities and exercise-real-time recordings of heart rate, respiration rate, energy intensity and other essential vital signs, as well as talking time and cadence, swallow counts and patterns, and other unconventional biomarkers. We also used the device in sleep laboratories and validated the measurements using polysomnography.

中文翻译：

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通过位于胸骨上切口的软无线设备，对生理过程和身体运动进行机械声学感应。

装有高带宽三轴加速度计的安装在皮肤上的软电子设备可以捕获广泛的生理相关信息，包括底层身体过程的机械声信号（例如用听诊器测量的信号）和核心身体运动的精确运动学。在这里，我们描述了一种无线设备，该设备被设计成保形地放置在胸骨上凹口上，用于连续测量机械声信号，从皮肤在加速度约为10-3 m s-2时的细微振动到整个身体的剧烈运动频率约为10 m s-2，频率高达800 Hz。由于测量结果是运动，身体朝向，吞咽，呼吸，心脏活动，声带振动和其他来源引起的信号的复杂叠加，我们利用频域分析和机器学习从自然日常活动中的人类受试者中获取心律，呼吸频率，能量强度和其他基本生命体征以及谈话时间和节奏，吞咽的运动实时记录计数和模式以及其他非常规生物标记。我们还在睡眠实验室中使用了该设备，并使用多导睡眠监测仪对测量结果进行了验证。